Olea South: (07) 3808 8624 | Olea North: (07) 3325 5512
Olea South: (07) 3808 8624
Olea North: (07) 3325 5512

Not all Brain Boosters are the SAMe

In Uncategorized

Introduced to the public around 20 years ago, this supplement was first tested in Italy as a treatment for schizophrenia in the 1970s.    However, while doing so, doctors noticed it also lifted the mood of their patients.   This set off a plethora of studies which were so successful, S-Adenosyl Methionine (SAMe) became a prescription drug for the treatment of depression in Italy, Germany, Spain and Russia.   SAMe is now available at Olea Health as a supplement.   The brain benefits of SAMe go well beyond being a safe, well-tolerated, fast-acting and effective anti-depressant, it is also a methylater.

Methylation and why we need it

SAMe is found in all body cells. It’s formed from the combination of the amino acid methionine with ATP, the main carrier of energy in cells.   ATP is the energy output from mitochondria, the cells’ little energy factories.   One of SAMe’s most prolific and important functions is to act as a methyl donor.   Methylation is a vital process that supports a great many biochemical reactions involved with gene expression, DNA repair, synthesis of proteins and neurotransmitters, fat and mineral metabolism, and maintaining cell membrane fluidity.   The ability to methylate declines as we get older, giving rise to an increased risk of neurodegeneration and other chronic diseases.

SAME may raise brain glutathione

Methylation involves a series of reactions, one of which creates glutathione. This is the body’s most important inside-the-cell antioxidant and detoxifier.   The brain is especially vulnerable to free radical assault because neurons lack high levels of antioxidant enzymes that depend on glutathione.

In an article published in the Annals of the New York Academy of Sciences, scientists conducted a number of studies involving Alzheimer’s patients. They concluded that “decreased glutathione content may be involved in Alzheimer’s disease pathology in humans.”

This is where SAMe comes in, because it can boost glutathione in the brain.   In a rodent study, SAMe decreased TBARS (harmful by products formed when free radicals damage fats) by 46% compared to controls. SAMe also increased glutathione levels by 50% and boosted two glutathione-dependent antioxidant enzymes in the brain by 115% and 81.4%.

SAMe may reduce the risk of Alzheimer’s

While low levels of SAMe are found in patients with depression, severely reduced amounts are found in those with Alzheimer’s.  One study found deficiencies of between 67% and 85% in eleven subjects post mortem.   Improved cognition following SAMe supplementation was found in several early studies, however more recently, SAMe demonstrated beneficial effects on the beta amyloid proteins and tau tangles associated with the disease.

In a mouse study, supplementation reduced the production and spread of amyloid, inhibited tau, and increased spatial memory (the animals’ ability to find their way round a maze)   In another study, beta amyloid brain deposits were reduced by 80% after just one month of treatment.   Scientists from The University of Massachusetts wrote in the Journal of Alzheimer’s Disease in 2008 that “dietary supplementation with S-adenosyl methionine alleviates a variety of risk factors and hallmarks associated with Alzheimer’s disease.”

May support better brain function in Parkinson’s

Researchers from Germany tested blood samples from 87 Parkinson’s patients whose average age was 68.   They found that markers of neurodegeneration such as amyloid are related to levels of SAMe, and better cognitive function was found in the patients with higher ratios.   The researchers tried administering SAMe to Parkinson’s patients who received either no benefit from antidepressant drugs or suffered intolerable side effects and found that SAMe reduced symptoms of depression by 65%, and concluded that SAMe “may be a safe and effective alternative” to antidepressants.

May promotes a better night’s sleep

SAMe is believed to work in its traditional role as an antidepressant by raising brain levels of melatonin and the neurotransmitters serotonin and dopamine. Low levels of these molecules are commonly found in mood disorders such as anxiety and depression, but serotonin and melatonin also play important roles in promoting sleep.   SAMe is able to raise melatonin levels by increasing the activity of the enzyme that converts serotonin to melatonin.    This major methylation reaction typically occurs around 9 pm to relax you and help you go to sleep.

SAMe is available as a supplement at Olea, but to optimize methylation it is best to also take vitamins B2, B6, B12, folic acid, vitamin D, magnesium and betaine (trimethylglycine) which is something our Naturopaths are trained to provide, and as we treat each patient as an individual, it’s time to make an appointment, get the supplements that are specific to you, and give your brain a boost!!

 


Contact Us

We're not around right now. But you can send us an email and we'll get back to you, asap.

Marketing Brisbane Brand Marketing Marketing Strategy Marketing Analytics Mobile Marketing Social Media Marketing B2B Marketing B2C Marketing Digital Marketing Content Marketing Email Marketing SEO Brisbane AdWords Management Facebook Advertising SEO Content Writing First Page of Google What is SEO What is Organic SEO One Page Websites Business Websites Ecommerce Websites SEO Pricing Facebook Pricing Email Marketing Pricing Free SEO Audit SEO Content Business Web Development SEO Brisbane Start A Business 2020 Grow Your Business Online Dominate The Market With SEO Online Marketing FAQs Social Media Marketing Brisbane SEO Brisbane SEO Geebung SEO Brendale SEO Banyo SEO North Lakes SEO Strathpine SEO Eagle Farm SEO North Brisbane SEO South Brisbane SEO West Brisbane SEO East Brisbane SEO Moorooka SEO Coopers Plains SEO Sunnybank SEO Springwood SEO Underwood SEO Slacks Creek SEO Logan Pay Per Click Advertising AdWords FAQs Content Writing FAQs Business Directory SEO Services & Digital Marketing Brisbane Marketing and SEO Brisbane SEO Brisbane Organic SEO Brisbane Google Ads Brisbane Local SEO Brisbane Social Media Brisbane SEO Services Brisbane SEO Consultant Brisbane SEO Company Brisbane SEO Brisbane Website Design Brisbane Website Developers Brisbane Website Designers Brisbane Website Developer Brisbane Website Development Brisbane Website Design Brisbane Website Designing Brisbane Cheap Website Design Brisbane eCommerce Website Design Brisbane SEO Website Brisbane Personal Website Design Brisbane Business Website Design Brisbane Entertainment Website Design Brisbane Portfolio Website Design Brisbane Non-Profit Website Design Brisbane Web Portal Website Design Brisbane Infopreneur Website Design Brisbane Educational Website Design Brisbane Brochure Website Design Brisbane SEO Consultant Brisbane SEO Services Brisbane SEO Services Gold Coast SEO Services Sunshine Coast SEO Services Sydney SEO Services Melbourne SEO Services Adelaide SEO Services Perth SEO Services Hobart SEO Services Canberra SEO Services Darwin A Frames Vinyl Banners Rectangle Flags Flyers Digital Print on ACM Sign Mesh Banners Lightboxes Window Graphics Wall Signage Parking Signs Illuminated Signs Digital Print on ACM Sign Car Wraps Car Magnets Stickers and Decals Custom Stickers NCR Booklets Envelopes Calendars Desk Pads Postcards Presentation Folders Letterhead Graphic Design Service Sign Installation Magnets Floor Graphics Large Format Stickers Acrylic Panel Signs Premium Pull-Up Banners Premium Business Cards PVC Plastic Business Cards Signage Signage Brisbane Building Signage Window Signage Signage Design Signage Installation Signage Printing Government Signage Transport and Main Roads Signage Tenders Signage Public Sector Signage Hospital Signage School Signage Medical Centre Signage Police Fire and Rescue Signage PCYC Signage Car Signage Signwriters Printing Printing Brisbane Government Printing Transport and Main Roads Printing Hospital Printing School Printing Medical Centre Printing Police Fire and Rescue Printing PCYC Printing Public Sector Printing Billboard and Signage Printing A Frame Printing Flags and Banner Printing Sticker Printing Display and Exhibition Printing Promotions and Events Printing Display Solutions Exhibition Display Stands Tradeshow Printing Flyer Design Business Card Printing Logo Design Car Wraps Commercial Wraps Van Wraps Ute Wraps Boat Wraps Trailer Wraps Van Wraps Full Car Wraps Partial Car Wraps Colour Change Wraps Carbon Fibre Wraps Paint Protection Wraps Window Wraps Trailer Wraps Wall Wraps Food Truck Wraps Printing Brisbane Car Wraps Gold Coast Car Wraps Sunshine Coast Car Wraps Brisbane Signage Brisbane Signage Gold Coast Signage Sunshine Coast Donate Now Donate To Qld Hospitals Donate To NSW Hospitals Donate To Vic Hospitals Donate To SA Hospitals Donate To WA Hospitals Donate To Tas Hospitals Donate To ACT Hospitals Donate To NT Hospitals Become A Corporate Ally Become A Wonder Worker Charity Fundraising Host A Fundraiser Leave A Bequest Critical Equipment Charities Best Charities To Donate To Kids Charity Australian Charities Queensland Charities Brisbane Charities New South Wales Charities Adelaide Charities South Australia Charities Melbourne Charities Victoria Charities Sydney Charities Western Australia Charities Perth Charities Tasmania Charities Hobart Charities Darwin Charities Northern Territory Charities Canberra Charities Australian Capital Territory Charities